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预测专科药物治疗服务的退出率和留存率的因素:英格兰西北部的一项病例对照研究

Factors predicting drop out from, and retention in, specialist drug treatment services: a case control study in the North West of England.

作者信息

Beynon Caryl M, McMinn Alison M, Marr Adam J E

机构信息

Centre for Public Health, Liverpool John Moores University, Liverpool, L3 2AY, UK.

出版信息

BMC Public Health. 2008 May 6;8:149. doi: 10.1186/1471-2458-8-149.

Abstract

BACKGROUND

In the United Kingdom (UK), the National Treatment Agency for Substance Misuse (NTA) considers retention to be the best available measure of drug treatment effectiveness. Accordingly, the NTA has set local treatment systems the annual target of retaining 75% of clients for 12 weeks or more, yet little assessment of this target or factors that improve retention has occurred. This study aims to quantify the proportion of people retained in treatment for 12 weeks in the North West of England and to identify factors associated with premature drop out.

METHODS

The North West National Drug Treatment Monitoring System (NDTMS) was used to identify treatment durations for everyone beginning a treatment episode between 1st April 2005 and 31st March 2006 (N = 16626). Odds ratios, chi-square and logistic regression analyses compared clients retained for 12 weeks to clients whose discharge record showed they had prematurely dropped out before 12 weeks. Individuals with other outcomes were excluded from analyses.

RESULTS

75% of clients (N = 12230) were retained for 12 weeks and 10% (N = 1649) dropped out prematurely. Multivariate analysis showed drop out was more likely among Asian drug users (adjusted odds ratio 1.52, 95% CI 1.12 to 2.08) than their white equivalents. Drop out was more likely among residents of Cumbria and Lancashire (adjusted odds ratio 1.80, 95% CI 1.51 to 2.15) and Greater Manchester (adjusted odds ratio 2.00, 95% CI 1.74 to 2.29) than Cheshire and Merseyside and less likely among alcohol users (adjusted odds ratio 0.73, 95% CI 0.59 to 0.91). A significant interaction between age and deprivation was observed. For those aged 18 to 24 years and 25 to 34 years, drop out was significantly more likely among those living in affluent areas. For those in the older age groups the converse effect was observed.

CONCLUSION

In combination, the drug treatment systems of the North West achieved the Government's retention target in 2005/06. A number of factors associated with drop out were identified; these should be considered in strategies that aim to improve retention. Drop out and retention are measures that capture the joint effect of many factors. Further work is required to evaluate the effect of deprivation.

摘要

背景

在英国,国家药物滥用治疗机构(NTA)认为治疗留存率是衡量药物治疗效果的最佳可用指标。因此,NTA为地方治疗系统设定了年度目标,即让75%的服务对象留存12周或更长时间,但对这一目标或提高留存率的因素几乎没有进行评估。本研究旨在量化英格兰西北部接受治疗12周的人员比例,并确定与过早退出相关的因素。

方法

利用西北部国家药物治疗监测系统(NDTMS)确定2005年4月1日至2006年3月31日期间开始治疗疗程的每个人的治疗时长(N = 16626)。通过比值比、卡方检验和逻辑回归分析,将留存12周的服务对象与出院记录显示在12周前过早退出的服务对象进行比较。其他结局的个体被排除在分析之外。

结果

75%的服务对象(N = 12230)留存了12周,10%(N = 1649)过早退出。多变量分析显示,亚洲吸毒者比白人吸毒者更有可能退出(调整后的比值比为1.52,95%置信区间为1.12至2.08)。坎布里亚郡和兰开夏郡(调整后的比值比为1.80,95%置信区间为1.51至2.15)以及大曼彻斯特地区(调整后的比值比为2.00,95%置信区间为1.74至2.29)的居民比柴郡和默西塞德郡的居民更有可能退出,而酗酒者退出的可能性较小(调整后的比值比为0.73,95%置信区间为0.59至0.91)。观察到年龄和贫困之间存在显著的交互作用。对于18至24岁和25至34岁的人群,生活在富裕地区的人退出的可能性显著更高。对于年龄较大的人群,则观察到相反的效果。

结论

综合来看,西北部的药物治疗系统在2005/06年度实现了政府的留存目标。确定了一些与退出相关的因素;在旨在提高留存率的策略中应考虑这些因素。退出和留存是反映多种因素共同作用的指标。需要进一步开展工作来评估贫困的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2709/2409325/7ddc82aaaaa4/1471-2458-8-149-1.jpg

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