Suppr超能文献

严重原发性产后出血、动脉栓塞与未来生育能力:46例回顾性研究

Serious primary post-partum hemorrhage, arterial embolization and future fertility: a retrospective study of 46 cases.

作者信息

Chauleur C, Fanget C, Tourne G, Levy R, Larchez C, Seffert P

机构信息

Department of Gynecology-Obstetrics, University Hospital NORD, F-42055 Saint-Etienne Cedex 2, France.

出版信息

Hum Reprod. 2008 Jul;23(7):1553-9. doi: 10.1093/humrep/den122. Epub 2008 May 6.

Abstract

BACKGROUND

The guidelines advise arterial embolization in case of post-partum hemorrhage. We evaluated its feasibility and the subsequent fertility.

METHODS

A retrospective study has been conducted in our center for the past 10 years (1996-2005). Fifty-two patients experiencing a primary post-partum hemorrhage who were resistant to medical treatment underwent uterine artery embolization and/or hysterectomy. In case of arterial embolization, a follow-up of all the patients was realized, focusing on the preservation of fertility.

RESULTS

Six (11.5%) patients underwent hysterectomy straightaway and 46 (88.5%) arterial embolization in the first instance including 35 arterial embolizations after Cesarean section. Embolization was successful among 41 patients (89.1%) and hysterectomy was performed on the 5 (10.9%) others. Overall, 11/24 398 women suffered from a definitive loss of fertility after post-partum hemorrhage. Fertility was studied at least 1 year after the delivery. All patients had a return of normal menses. Sixteen of 41 women (39%) wanted another child and 100% succeeded. Nineteen pregnancies, including two twin pregnancy and one early spontaneous abortion were observed.

CONCLUSIONS

Embolization is a safe and effective non-surgical method to resolve post-partum hemorrhage and should be regarded as gold standard in a hemodynamically stable patient. Furthermore, subsequent fertility is not impaired by the procedure.

摘要

背景

指南建议在产后出血时进行动脉栓塞。我们评估了其可行性及对后续生育能力的影响。

方法

在我们中心对过去10年(1996 - 2005年)进行了一项回顾性研究。52例原发性产后出血且药物治疗无效的患者接受了子宫动脉栓塞和/或子宫切除术。对于接受动脉栓塞的患者,对所有患者进行了随访,重点关注生育能力的保留情况。

结果

6例(11.5%)患者立即接受了子宫切除术,46例(88.5%)首先接受了动脉栓塞,其中包括35例剖宫产术后的动脉栓塞。41例患者(89.1%)栓塞成功,另外5例(10.9%)接受了子宫切除术。总体而言,24398名女性中有11名在产后出血后永久性丧失生育能力。在分娩后至少1年对生育能力进行了研究。所有患者月经恢复正常。41名女性中有16名(39%)想要再要一个孩子,且100%成功。观察到19次妊娠,包括2次双胎妊娠和1次早期自然流产。

结论

栓塞是一种安全有效的解决产后出血的非手术方法,对于血流动力学稳定的患者应被视为金标准。此外,该手术不会损害后续生育能力。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验