Huang Sheng-Teng, Chen Annie Pei-Chun
Department of Chinese Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung Institute of Technology, Taiwan, ROC.
Curr Opin Obstet Gynecol. 2008 Jun;20(3):211-5. doi: 10.1097/GCO.0b013e3282f88e22.
The present review gives an overview of the potential use of traditional Chinese medicine in the treatment of infertility, including an evidence-based evaluation of its efficacy and tolerance.
Recent studies demonstrated that traditional Chinese medicine could regulate the gonadotropin-releasing hormone to induce ovulation and improve the uterus blood flow and menstrual changes of endometrium. In addition, it also has impacts on patients with infertility resulting from polycystic ovarian syndrome, anxiety, stress and immunological disorders. Although study design with adequate sample size and appropriate control for the use of traditional Chinese medicine is not sufficient, the effective studies have already indicated the necessity to explore the possible mechanisms, that is, effective dose, side effect and toxicity of traditional Chinese medicine, in the treatment of infertility by means of prospective randomized control trial.
The growing popularity of traditional Chinese medicine used alone or in combination with Western medicine highlights the need to examine the pros and cons of both Western and traditional Chinese medicine approaches. Integrating the principle and knowledge from well characterized approaches and quality control of both traditional Chinese medicine and Western medical approaches should become a trend in existing clinical practice and serve as a better methodology for treating infertility.
本综述概述了中药在治疗不孕症方面的潜在用途,包括对其疗效和耐受性的循证评估。
近期研究表明,中药可调节促性腺激素释放激素以诱导排卵,并改善子宫血流及子宫内膜的月经变化。此外,它对多囊卵巢综合征、焦虑、压力和免疫紊乱导致的不孕症患者也有影响。尽管针对中药使用的样本量充足且对照合适的研究设计尚不充分,但有效研究已表明有必要通过前瞻性随机对照试验探索中药治疗不孕症的可能机制,即有效剂量、副作用和毒性。
单独使用或与西药联合使用的中药越来越受欢迎,这凸显了审视西药和中药方法优缺点的必要性。将中医和西医方法中特征明确的方法、原理及知识与质量控制相结合,应成为现有临床实践的趋势,并作为治疗不孕症的更好方法。