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肾移植后的生殖与避孕

Reproduction and contraception after kidney transplantation.

作者信息

Watnick Suzanne, Rueda Jose

机构信息

Department of Medicine, Oregon Health & Science University, Portland, Oregon, USA.

出版信息

Curr Opin Obstet Gynecol. 2008 Jun;20(3):308-12. doi: 10.1097/GCO.0b013e3282f8b009.

Abstract

PURPOSE OF REVIEW

In this manuscript we review the most recent data regarding birth rates and complications in the kidney transplant population. Despite improved fertility, contraceptive counseling is infrequent and contraceptive use engenders many problems not frequently seen in women of childbearing age.

RECENT FINDINGS

Pregnancy outcomes in this population are improving, but these patients are still considered 'high risk'. With improved fertility after transplantation, contraception should be viewed as essential in those who wish to avoid pregnancy. Many forms of contraception are viable for women with a kidney transplant.

SUMMARY

Given increased rates of preeclampsia, preterm delivery, low birth weight, and increased risk of cesarean section, a multidisciplinary team must be involved, which will tend to everything from general fetal and maternal monitoring, serial measurement of kidney function, and medication adjustment. For all these reasons, contraceptive counseling is necessary for all women of childbearing age, both pre and posttransplantation. Specific methods of contraception can be individualized to a patient's needs and should be discussed between patient and provider. Future study of both reproduction and contraception use in kidney transplant recipients is sorely needed.

摘要

综述目的

在本手稿中,我们回顾了有关肾移植人群出生率和并发症的最新数据。尽管生育能力有所提高,但避孕咨询并不常见,且避孕措施的使用引发了许多在育龄女性中不常见的问题。

最新发现

该人群的妊娠结局正在改善,但这些患者仍被视为“高危”人群。随着移植后生育能力的提高,对于那些希望避免怀孕的人来说,避孕应被视为至关重要的。多种避孕方式对肾移植女性都是可行的。

总结

鉴于子痫前期、早产、低出生体重的发生率增加以及剖宫产风险升高,必须有一个多学科团队参与其中,该团队要负责从一般的胎儿和母体监测、肾功能的系列测量到药物调整等所有事项。出于所有这些原因,对所有育龄女性,无论移植前还是移植后,避孕咨询都是必要的。具体的避孕方法可以根据患者的需求进行个体化定制,并且应该由患者和医疗服务提供者共同讨论。肾移植受者生殖和避孕使用方面的未来研究非常必要。

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