[黏液性卵巢肿瘤导致的母体男性化：一例报告]

[Maternal virilization due to mucinous ovarian tumour: a case report].

作者信息

Fanara E, Darnis E, Winer N, Kandel C, Laboisse C, Philippe H-J

机构信息

Service de gynécologie-obstétrique et médecine foetale, hôpital Mère-Enfants, CHU de Nantes, 38, boulevard Jean-Monnet, 44093 Nantes cedex, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2008 Sep;37(5):524-7. doi: 10.1016/j.jgyn.2008.02.006. Epub 2008 May 6.

DOI:10.1016/j.jgyn.2008.02.006

PMID:18462892

Abstract

Virilization in pregnancy is rare and mostly due to luteoma or to hyper-reactio luteinalis. We present a rare case of a virilization borderline mucinous ovarian tumour on a gravida 1 patient. The tumour was responsible for a clinical hyperandrogenism and for an increased level of testosterone. This patient was treated by ovariectomy at 31 weeks of gestation. The surgery was completed one month after delivery. There was no fetal consequence and the clinical and biological signs of virilization totally disappeared after surgery.

摘要

妊娠期男性化较为罕见，主要由黄体瘤或黄素化囊肿过度反应引起。我们报告一例罕见的初孕妇患有男性化的交界性黏液性卵巢肿瘤。该肿瘤导致临床高雄激素血症及睾酮水平升高。此患者在妊娠31周时接受了卵巢切除术。手术在产后一个月完成。未对胎儿造成影响，术后男性化的临床及生物学体征完全消失。