Acaroglu Golge, Akinci Arsen, Zilelioglu Orhan
Department of Neuroophthalmology, Ministry of Health Ulucanlar Eye Hospital, Ankara, Turkey.
Ophthalmologica. 2008;222(4):225-8. doi: 10.1159/000130070. Epub 2008 May 8.
To compare patients with palsy of the 3rd, 4th or 6th cranial nerve due to diabetes mellitus (DM) with controls matched for age, sex and disease duration in terms of the presence and severity of diabetic retinopathy.
Thirty-three diabetic patients with cranial nerve palsies and 33 age- and sex-matched controls with the same duration of disease were included in this case-control study. Groups were evaluated in terms of the type of DM, presence and level of diabetic retinopathy and coexisting systemic diseases. Outcomes were compared by chi(2) and paired-sample tests.
Eleven patients had diabetic retinopathy in the study group. In the control group, 23 patients had diabetic retinopathy. Differences in the presence and severity of diabetic retinopathy between the two groups were found to be statistically significant (p = 0.028 and p = 0.018, respectively).
Presence and level of diabetic retinopathy are significantly lower in diabetics with cranial nerve palsy than in the age-, sex- and disease-duration-matched controls.
比较因糖尿病(DM)导致动眼神经、滑车神经或展神经麻痹的患者与年龄、性别和病程相匹配的对照组在糖尿病视网膜病变的存在情况和严重程度方面的差异。
本病例对照研究纳入了33例患有颅神经麻痹的糖尿病患者以及33例年龄、性别匹配且病程相同的对照者。对两组患者的糖尿病类型、糖尿病视网膜病变的存在情况和程度以及并存的全身性疾病进行评估。通过卡方检验和配对样本检验比较结果。
研究组中有11例患者患有糖尿病视网膜病变。对照组中有23例患者患有糖尿病视网膜病变。发现两组之间糖尿病视网膜病变的存在情况和严重程度差异具有统计学意义(分别为p = 0.028和p = 0.018)。
患有颅神经麻痹的糖尿病患者的糖尿病视网膜病变存在情况和程度显著低于年龄、性别和病程相匹配的对照组。