Slade D Snow, Johnson Jonathan T, Tabin Geoffrey
John Moran Eye Center, Department of Ophthalmology and Vision Sciences, University of Utah School of Medicine, Salt Lake City, UT, USA.
Eye Contact Lens. 2008 May;34(3):185-7. doi: 10.1097/ICL.0b013e3181506ad1.
To report a case of corneal perforation secondary to Acanthamoeba and fungal keratitis in a patient with a history of Intacs corneal implants.
The patient's history, clinical presentation, and pathologic analysis were reviewed.
A 56-year-old woman with keratoconus was referred to the university eye center for a corneal perforation secondary to a chronic corneal ulcer initially diagnosed as herpes simplex keratitis. The patient had Intacs inserted in the same eye 14 months earlier, but had them removed approximately 1 month before her visit. After emergency keratoplasty, the patient's corneal tissue was sent for histopathologic examination, which showed an Acanthamoeba and fungal coinfection.
Atypical sources of keratitis should be considered in patients with a chronic corneal ulcer and a history of Intacs corneal implants.
报告一例有Intacs角膜植入物病史的患者继发棘阿米巴和真菌性角膜炎导致角膜穿孔的病例。
回顾患者的病史、临床表现及病理分析。
一名56岁圆锥角膜女性因慢性角膜溃疡继发角膜穿孔被转诊至大学眼科中心,该角膜溃疡最初诊断为单纯疱疹性角膜炎。患者14个月前在同一只眼植入了Intacs,但在就诊前约1个月将其取出。紧急角膜移植术后,患者的角膜组织送去做组织病理学检查,结果显示为棘阿米巴和真菌混合感染。
对于有慢性角膜溃疡且有Intacs角膜植入物病史的患者,应考虑非典型的角膜炎病因。