Solis A, Baillard C
Unité d'anesthésie-réanimation, hôpital Avicenne, 125, route de Stalingrad, 93009 Bobigny, France.
Ann Fr Anesth Reanim. 2008 Jun;27(6):490-4. doi: 10.1016/j.annfar.2008.04.006. Epub 2008 May 7.
The purpose of this article was to present an update of the preoxygenation management in morbidly obese adults, parturient women and hypoxemic critically-ill patients.
All references obtained from the medical database Medline related to the area and more specifically during the last five years were reviewed.
Preoxygenation decreases the risk of hypoxia and should be optimized when the standard technique appears to be less effective as in morbidly obese adults, parturient women and critically-ill patients. The head-up position and noninvasive ventilation may be useful during preoxygenation probably because of the increase of ventilation and alveolar recruitment. The effectiveness of preoxygenation (when defined as the duration of the desaturation safety period) is enhanced in the head-up position as compared to supine position in the obese patient but not in parturient women. Noninvasive ventilation improves preoxygenation in the hypoxemic critically-ill patient but not in the obese patient. Neither the head-up position nor the noninvasive ventilation improve preoxygenation in parturient women.
Further studies are required to investigate other methods attempting to improve preoxygenation and prevent hypoxemia during intubation.
本文旨在介绍病态肥胖成年人、产妇及低氧血症危重症患者预充氧管理的最新情况。
对从医学数据库Medline获取的、与该领域相关的所有参考文献进行了回顾,尤其关注了过去五年间的文献。
预充氧可降低缺氧风险,当标准技术在病态肥胖成年人、产妇及危重症患者中效果欠佳时,应进行优化。头高位和无创通气在预充氧过程中可能有用,这可能是由于通气增加和肺泡复张。与仰卧位相比,肥胖患者采用头高位时预充氧效果(定义为去饱和安全期的持续时间)更佳,但产妇并非如此。无创通气可改善低氧血症危重症患者的预充氧,但对肥胖患者无效。头高位和无创通气均不能改善产妇的预充氧。
需要进一步研究以探索其他方法,试图改善预充氧并预防插管期间的低氧血症。