转座元件在锥虫中的作用。

Role of transposable elements in trypanosomatids.

作者信息

Bringaud Frédéric, Ghedin Elodie, El-Sayed Najib M A, Papadopoulou Barbara

机构信息

Laboratoire de Résonance Magnétique des Systèmes Biologiques, Université Victor Segalen Bordeaux 2, UMR-5536 CNRS, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France.

出版信息

Microbes Infect. 2008 May;10(6):575-81. doi: 10.1016/j.micinf.2008.02.009. Epub 2008 Feb 21.

DOI:10.1016/j.micinf.2008.02.009

PMID:18467144

Abstract

Transposable elements constitute 2-5% of the genome content in trypanosomatid parasites. Some of them are involved in critical cellular functions, such as the regulation of gene expression in Leishmania spp. In this review, we highlight the remarkable role extinct transposable elements can play as the source of potential new functions.

摘要

转座元件在锥虫寄生虫的基因组中占2%-5%。其中一些转座元件参与关键的细胞功能，比如利什曼原虫属中基因表达的调控。在这篇综述中，我们强调了已灭绝的转座元件作为潜在新功能来源可能发挥的显著作用。