Nystod Tove, Utsi Egil, Selmer Randi, Brox Jan, Melhus Marita, Lund Eiliv
Centre for Sami Health Research, Institute of Community Medicine, University of Tromsø, NO-9037 Tromsø, Norway.
Int J Circumpolar Health. 2008 Feb;67(1):67-81.
To assess the distribution of blood lipids, lipoprotein and apoB/apoA-1 ratio in a multi-ethnic population of Sami, Kvens and Norwegians in Norway. Study design. A population-based cross-sectional study was carried out in 2003-2004 in an area with a mixed Sami, Kvens/Finns and Norwegian population, the SAMINOR study.
A self-administrated questionnaire was distributed and total cholesterol, HDL cholesterol, triglycerides, apoB and apoA-1 counts were analysed in 6461 women and 5772 men between the ages of 36 and 79.
In 36-64 age group, Sami men and women had the highest apoB/apoA-1 ratio of the ethnic groups. The ethnic differences remained after adjustment for waist hip ratio, cigarette smoking, systolic and diastolic pressures, alcohol consumption, physical activity during leisure time and family history of myocardial infarction (MI). There were no significant ethnic differences in apoB/apoA-1 ratio in the older age group. Total cholesterol was significantly lower among Sami men and women, aged 65-79 years, than among the Norwegian. The opposite occurred in the 36-49 age group, with higher levels in the Sami population. We found no ethnic differences in HDL cholesterol and triglycerides.
Middle-aged Sami women and men have increased levels of apoB/apoA-1 ratio and total cholesterol compared with Norwegians.
评估挪威萨米人、克文人及挪威人这一多民族人群的血脂、脂蛋白分布及载脂蛋白B/载脂蛋白A-1比值。研究设计。2003年至2004年在一个萨米人、克文人/芬兰人和挪威人混居的地区开展了一项基于人群的横断面研究,即萨米诺尔研究。
发放一份自填式问卷,并对6461名年龄在36至79岁之间的女性和5772名年龄在36至79岁之间的男性进行总胆固醇、高密度脂蛋白胆固醇、甘油三酯、载脂蛋白B和载脂蛋白A-1计数分析。
在36至64岁年龄组中,萨米族男性和女性的载脂蛋白B/载脂蛋白A-1比值在各民族中最高。在对腰臀比、吸烟、收缩压和舒张压、饮酒、休闲时间身体活动及心肌梗死家族史进行调整后,种族差异依然存在。在老年组中,载脂蛋白B/载脂蛋白A-1比值没有显著的种族差异。65至79岁的萨米族男性和女性的总胆固醇显著低于挪威人。在36至49岁年龄组中情况相反,萨米族人群的总胆固醇水平更高。我们发现高密度脂蛋白胆固醇和甘油三酯没有种族差异。
与挪威人相比,中年萨米族女性和男性的载脂蛋白B/载脂蛋白A-1比值及总胆固醇水平有所升高。