Górka B, Nilsson B, Svensson R, Brahme A, Ascarelli P, Trucchi D M, Conte G, Kalish R
Medical Radiation Physics, Department of Oncology and Pathology, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
Phys Med. 2008 Sep;24(3):159-68. doi: 10.1016/j.ejmp.2008.03.003. Epub 2008 May 12.
New solid-state detectors, based on chemical vapour deposited (CVD) polycrystalline diamonds produced by hot-filament (HF) or microwave plasma (MW) assisted deposition methods, were constructed for radiation therapy dosimetry. Properties of diamond crystals, such as high radiation sensitivity, resistance to radiation damage and tissue-equivalence giving a low-energy dependence are very advantageous for clinical dosimetry. Therefore the encapsulation was specially designed for these detectors to have as little influence as possible on the radiation response. The prototypes were irradiated with use of a wide range of photon beam qualities ((60)Co gamma-rays, 6 and 18 MV X-rays). The radiation sensitivity varied considerably between samples deposited with HF (9 nC Gy(-1)mm(-3)) and MW (66 and 144 nC Gy(-1)mm(-3)) methods. For all detectors the leakage current was of the order of 10% of the radiation-induced current (bias voltage 100 V, dose rate 0.3 Gy/min). When irradiated with (60)Co gamma-rays, the detectors showed a dose-rate linearity with an exponential Delta parameter close to unity. However, a difference of 8% was found between Delta values for the different beam qualities. A small energy dependence was observed, for which the most probable sources are interface effects due to the silver electrodes and partly the geometry of the encapsulation which needs to be further optimized. Despite some limitations in the performance of present prototype detectors, with an improved CVD technique producing crystals of better electrical and dosimetric properties, and with a well-designed tissue-equivalent encapsulation, CVD-diamonds could serve as very good dosimeters for radiotherapy.
基于通过热丝(HF)或微波等离子体(MW)辅助沉积方法制备的化学气相沉积(CVD)多晶金刚石构建了新型固态探测器,用于放射治疗剂量测定。金刚石晶体的特性,如高辐射敏感性、抗辐射损伤以及具有低能量依赖性的组织等效性,对于临床剂量测定非常有利。因此,专门为这些探测器设计了封装,使其对辐射响应的影响尽可能小。使用多种光子束质量((60)Coγ射线、6和18MV X射线)对原型进行了辐照。用HF(9nC Gy(-1)mm(-3))和MW(66和144nC Gy(-1)mm(-3))方法沉积的样品之间,辐射敏感性差异很大。对于所有探测器,漏电流约为辐射诱导电流的10%(偏置电压100V,剂量率0.3Gy/min)。当用(60)Coγ射线辐照时,探测器显示出剂量率线性,指数Δ参数接近1。然而,不同束质量的Δ值之间发现有8%的差异。观察到存在小的能量依赖性,最可能的来源是银电极引起的界面效应以及部分封装的几何形状,这需要进一步优化。尽管目前的原型探测器在性能上存在一些局限性,但随着改进的CVD技术能够生产出具有更好电学和剂量学性能的晶体,以及精心设计的组织等效封装,CVD金刚石可作为放射治疗的非常好的剂量计。