Górka B, Nilsson B, Fernández-Varea J M, Svensson R, Brahme A
Medical Radiation Physics, Department of Oncology and Pathology, Karolinska Institutet and Stockholm University, Box 260, 171 76 Stockholm, Sweden.
Phys Med Biol. 2006 Aug 7;51(15):3607-23. doi: 10.1088/0031-9155/51/15/001. Epub 2006 Jul 12.
A new dosimeter, based on chemical vapour deposited (CVD) diamond as the active detector material, is being developed for dosimetry in radiotherapeutic beams. CVD-diamond is a very interesting material, since its atomic composition is close to that of human tissue and in principle it can be designed to introduce negligible perturbations to the radiation field and the dose distribution in the phantom due to its small size. However, non-tissue-equivalent structural components, such as electrodes, wires and encapsulation, need to be carefully selected as they may induce severe fluence perturbation and angular dependence, resulting in erroneous dose readings. By introducing metallic electrodes on the diamond crystals, interface phenomena between high- and low-atomic-number materials are created. Depending on the direction of the radiation field, an increased or decreased detector signal may be obtained. The small dimensions of the CVD-diamond layer and electrodes (around 100 microm and smaller) imply a higher sensitivity to the lack of charged-particle equilibrium and may cause severe interface phenomena. In the present study, we investigate the variation of energy deposition in the diamond detector for different photon-beam qualities, electrode materials and geometric configurations using the Monte Carlo code PENELOPE. The prototype detector was produced from a 50 microm thick CVD-diamond layer with 0.2 microm thick silver electrodes on both sides. The mean absorbed dose to the detector's active volume was modified in the presence of the electrodes by 1.7%, 2.1%, 1.5%, 0.6% and 0.9% for 1.25 MeV monoenergetic photons, a complete (i.e. shielded) (60)Co photon source spectrum and 6, 18 and 50 MV bremsstrahlung spectra, respectively. The shift in mean absorbed dose increases with increasing atomic number and thickness of the electrodes, and diminishes with increasing thickness of the diamond layer. From a dosimetric point of view, graphite would be an almost perfect electrode material. This study shows that, for the considered therapeutic beam qualities, the perturbation of the detector signal due to charge-collecting graphite electrodes of thicknesses between 0.1 and 700 microm is negligible within the calculation uncertainty of 0.2%.
一种基于化学气相沉积(CVD)金刚石作为活性探测器材料的新型剂量计正在被开发用于放射治疗束的剂量测定。CVD金刚石是一种非常有趣的材料,因为其原子组成与人体组织相近,并且原则上由于其尺寸小,可设计为对体模中的辐射场和剂量分布引入可忽略不计的扰动。然而,非组织等效的结构部件,如电极、导线和封装,需要仔细选择,因为它们可能会引起严重的注量扰动和角度依赖性,从而导致剂量读数错误。通过在金刚石晶体上引入金属电极,会产生高原子序数和低原子序数材料之间的界面现象。根据辐射场的方向,可能会获得增加或减少的探测器信号。CVD金刚石层和电极的小尺寸(约100微米及更小)意味着对缺乏带电粒子平衡具有更高的灵敏度,并且可能会导致严重的界面现象。在本研究中,我们使用蒙特卡罗代码PENELOPE研究了不同光子束质量、电极材料和几何配置下金刚石探测器中能量沉积的变化。原型探测器由一个50微米厚的CVD金刚石层制成,两侧有0.2微米厚的银电极。对于1.25 MeV单能光子、完整(即屏蔽)的(60)Co光子源谱以及6、18和50 MV轫致辐射谱,在有电极的情况下,探测器活性体积的平均吸收剂量分别改变了1.7%、2.1%、1.5%、0.6%和0.9%。平均吸收剂量的偏移随着电极原子序数和厚度的增加而增加,并随着金刚石层厚度的增加而减小。从剂量学角度来看,石墨将是一种几乎完美的电极材料。这项研究表明,对于所考虑的治疗束质量,厚度在0.1至700微米之间的电荷收集石墨电极引起的探测器信号扰动在0.2%的计算不确定度内可忽略不计。