Genome. 1995 Apr;38(2):283-9. doi: 10.1139/g95-035.
Gametocidal (Gc) genes in Aegilops species are known to cause gamete abortion and chromosome breakage when they are introduced into the wheat genetic background. Interactions of five Gc genes so far identified were investigated by analysis of wheat hybrids among lines carrying different gametocidal genes. As a result, the genes were classified into three functional groups. The first group includes two Gc genes of Ae. speltoides (Gc1a and Gc1b) and one gene (Gc-Sl3) on chromosome 2S1 of Ae. sharonensis. These genes were hypostatic to the genes (Gc-Sl1, Gc-Sl2) on chromosome 4S1 of Ae. longissima and Ae. sharonensis, which constitute the second group. In addition, plants carrying Gc genes of both the first and the second group produced progeny with higher frequencies of chromosome breakage than those found in the progeny of single gene carriers. It was concluded that there were specific interactions between these genes to enhance chromosome breakage. On the other hand, there was no interaction between the Gc gene (Gc-C) of Ae. triuncialis, the third group, and Gc genes belonging to the former two groups. These functional groups might be a reflection of the mechanisms by which Gc genes induce gamete abortion and chromosome breakage. Based on functional and local relationships, the symbols of the Gc genes were systematically redesignated.
已知在小麦遗传背景中导入 Aegilops 物种中的配子杀伤（Gc）基因时，会导致配子流产和染色体断裂。通过分析携带不同配子杀伤基因的小麦杂种，研究了迄今为止鉴定的五个 Gc 基因的相互作用。结果，这些基因被分为三个功能组。第一组包括 Ae. speltoides 的两个 Gc 基因（Gc1a 和 Gc1b）和 Ae. sharonensis 2S1 染色体上的一个基因（Gc-Sl3）。这些基因与 Ae. longissima 和 Ae. sharonensis 4S1 染色体上的基因（Gc-Sl1、Gc-Sl2）处于同一位置，构成第二组。此外，携带第一组和第二组 Gc 基因的植物比携带单个基因的植物的后代产生更高频率的染色体断裂。结论是这些基因之间存在特定的相互作用，以增强染色体断裂。另一方面，Ae. triuncialis 的 Gc 基因（Gc-C）与前两组的 Gc 基因之间没有相互作用。这些功能组可能反映了 Gc 基因诱导配子流产和染色体断裂的机制。基于功能和局部关系，对 Gc 基因的符号进行了系统重新命名。
