大肠杆菌对乙二胺四乙酸（EDTA）的摄取与降解

Uptake and degradation of EDTA by Escherichia coli.

作者信息

Suzuki Yousuke, Koyama Noriyuki

机构信息

Department of Chemistry, Faculty of Science, Chiba University, Yayoi, Chiba, Japan.

出版信息

Biodegradation. 2009 Feb;20(1):39-44. doi: 10.1007/s10532-008-9197-z. Epub 2008 May 11.

DOI:10.1007/s10532-008-9197-z

PMID:18470656

Abstract

It was found that Escherichia coli exhibited a growth by utilization of Fe(III)EDTA as a sole nitrogen source. No significant growth was detected when Fe(III)EDTA was replaced by EDTA complexes with other metal ions such as Ca(2+), Co(2+), Cu(2+), Mg(2+), Mn(2+), and Zn(2+). When EDTA uptake was measured in the presence of various ions, it was remarkable only when Fe(3+) was present. The cell extract of E. coli exhibited a significant degradation of EDTA only in the presence of Fe(3+). It is likely that the capability of E. coli for the growth by utilization of Fe(III)EDTA results from the Fe(3+)-dependent uptake and degradation of EDTA.

摘要

研究发现，大肠杆菌能够利用Fe(III)EDTA作为唯一氮源进行生长。当用EDTA与其他金属离子如Ca(2+)、Co(2+)、Cu(2+)、Mg(2+)、Mn(2+)和Zn(2+)形成的络合物取代Fe(III)EDTA时，未检测到显著生长。当在各种离子存在的情况下测量EDTA摄取时，只有在存在Fe(3+)时才显著。大肠杆菌的细胞提取物仅在存在Fe(3+)时才表现出EDTA的显著降解。大肠杆菌利用Fe(III)EDTA进行生长的能力可能源于Fe(3+)依赖的EDTA摄取和降解。