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AMPK与Raptor:使细胞生长与能量供应相匹配

AMPK and Raptor: matching cell growth to energy supply.

作者信息

Hardie D Grahame

机构信息

Division of Molecular Physiology, College of Life Science, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.

出版信息

Mol Cell. 2008 May 9;30(3):263-5. doi: 10.1016/j.molcel.2008.04.012.

DOI:10.1016/j.molcel.2008.04.012
PMID:18471972
Abstract

In a recent issue of Molecular Cell, Gwinn et al. (2008) suggest a novel mechanism by which AMPK signals to mTOR, and they provide new insight into how information about cellular energy status is fed into decisions about cell growth and proliferation.

摘要

在最近一期的《分子细胞》杂志上,格温等人(2008年)提出了一种新的机制,通过该机制AMPK向mTOR发出信号,并且他们对细胞能量状态信息如何输入到细胞生长和增殖决策中提供了新的见解。

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