Webb W R, Gatsonis C, Zerhouni E A, Heelan R T, Glazer G M, Francis I R, McNeil B J
Department of Diagnostic Radiology, University of California, San Francisco 94143-0628.
Radiology. 1991 Mar;178(3):705-13. doi: 10.1148/radiology.178.3.1847239.
The accuracies of magnetic resonance (MR) imaging and computed tomography (CT) in determining tumor classification and assessing mediastinal node metastases were compared in a prospective cooperative study of 170 patients with non-small cell bronchogenic carcinoma. The sensitivity of CT in distinguishing T3-T4 tumors from T0-T2 tumors was 63%; specificity was 84%. These values for MR imaging were not significantly different (56% and 80%). With receiver operating characteristic (ROC) analysis, no difference existed between the accuracies of CT and MR imaging in diagnosis of bronchial involvement or chest wall invasion, but MR imaging was significantly more accurate than CT (P = .047) in diagnosis of mediastinal invasion. Lymph node sampling was performed in 155 patients (642 node stations). Cancerous nodes were found in 14% of stations in 21% of patients. There was no significant difference between the accuracies of CT and MR imaging in detecting mediastinal node metastases (N2 or N3); the sensitivities were 52% and 48%, respectively, and specificities were 69% and 64%. ROC analysis also showed no difference between CT and MR imaging.
在一项针对170例非小细胞支气管癌患者的前瞻性合作研究中，对磁共振成像（MR）和计算机断层扫描（CT）在确定肿瘤分类及评估纵隔淋巴结转移方面的准确性进行了比较。CT区分T3 - T4期肿瘤与T0 - T2期肿瘤的敏感性为63%；特异性为84%。MR成像的这些值无显著差异（分别为56%和80%）。通过受试者操作特征（ROC）分析，CT和MR成像在诊断支气管受累或胸壁侵犯的准确性方面无差异，但在诊断纵隔侵犯方面，MR成像显著比CT更准确（P = 0.047）。对155例患者（642个淋巴结站）进行了淋巴结采样。在21%的患者中，14%的淋巴结站发现有癌性淋巴结。CT和MR成像在检测纵隔淋巴结转移（N2或N3）的准确性方面无显著差异；敏感性分别为52%和48%，特异性分别为69%和64%。ROC分析也显示CT和MR成像之间无差异。
