Goodlin Sarah J, Wingate Sue, Pressler Susan J, Teerlink John R, Storey C Porter
Patient-centered Education and Research, Salt Lake City, Utah, USA.
J Card Fail. 2008 May;14(4):276-82. doi: 10.1016/j.cardfail.2008.01.008.
Heart failure is a major cause of morbidity and mortality and is increasing in prevalence. Treatments for heart failure permit a growing number of persons to live with the illness for many years. The burden of symptoms in persons with advanced heart failure is high. Fatigue, limited exertion, dyspnea, and depression are commonly associated with heart failure, but pain is common as well.
Although it is known that underlying comorbidities modify the response to and experience of pain, the interaction between pain and the clinical syndrome of heart failure has not been studied to date. The Pain Assessment, Incidence & Nature in Heart Failure (PAIN-HF) study will evaluate pain in patients with advanced heart failure. Specifically, PAIN-HF will examine the anatomical location of pain, prevalence of pain, its association with aspects of patients' heart failure and comorbid conditions, and its relation to interventions and medications to treat pain.
This study to identify the nature, incidence, and character of pain is an important step in relieving distress and discomfort in persons with heart failure.
心力衰竭是发病和死亡的主要原因，且患病率正在上升。心力衰竭的治疗使越来越多的人能够带病生存多年。晚期心力衰竭患者的症状负担很重。疲劳、活动受限、呼吸困难和抑郁通常与心力衰竭有关，但疼痛也很常见。
虽然已知潜在的合并症会改变对疼痛的反应和体验，但迄今为止，疼痛与心力衰竭临床综合征之间的相互作用尚未得到研究。心力衰竭疼痛评估、发病率及性质（PAIN-HF）研究将评估晚期心力衰竭患者的疼痛情况。具体而言，PAIN-HF将检查疼痛的解剖位置、疼痛患病率、其与患者心力衰竭及合并症各方面的关联，以及其与疼痛治疗干预措施和药物的关系。
这项旨在确定疼痛的性质、发病率和特征的研究，是缓解心力衰竭患者痛苦和不适的重要一步。
