Wehe André, Bansal Mukul S, Burleigh J Gordon, Eulenstein Oliver
Department of Computer Science, Iowa State University, Ames, IA 50011, USA.
Bioinformatics. 2008 Jul 1;24(13):1540-1. doi: 10.1093/bioinformatics/btn230. Epub 2008 May 12.
DupTree is a new software program for inferring rooted species trees from collections of gene trees using the gene tree parsimony approach. The program implements a novel algorithm that significantly improves upon the run time of standard search heuristics for gene tree parsimony, and enables the first truly genome-scale phylogenetic analyses. In addition, DupTree allows users to examine alternate rootings and to weight the reconciliation costs for gene trees. DupTree is an open source project written in C++.
DupTree for Mac OS X, Windows, and Linux along with a sample dataset and an on-line manual are available at http://genome.cs.iastate.edu/CBL/DupTree
DupTree是一款新的软件程序,用于使用基因树简约法从基因树集合中推断有根物种树。该程序实现了一种新颖的算法,该算法显著改进了基因树简约法标准搜索启发式算法的运行时间,并实现了首次真正的全基因组规模系统发育分析。此外,DupTree允许用户检查不同的根定位,并对基因树的和解成本进行加权。DupTree是一个用C++编写的开源项目。
适用于Mac OS X、Windows和Linux的DupTree以及一个示例数据集和在线手册可在http://genome.cs.iastate.edu/CBL/DupTree获得。