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下咽及颈段食管癌切除术后游离空肠移植与胃上提重建的比较。

Comparison of free jejunal graft with gastric pull-up reconstruction after resection of hypopharyngeal and cervical esophageal carcinoma.

作者信息

Ferahkose Z, Bedirli A, Kerem M, Azili C, Sozuer E M, Akin M

机构信息

Gazi University Medical Faculty, Department of General Surgery, Ankara, Turkey.

出版信息

Dis Esophagus. 2008;21(4):340-5. doi: 10.1111/j.1442-2050.2007.00781.x.

Abstract

The purpose of this study is to evaluate the operative outcomes of a gastric pull-up and free jejunal graft reconstruction after resection of hypopharyngeal and cervical esophageal carcinoma. Records of all patients who underwent esophageal resection for carcinoma of the hypopharynx and cervical esophagus were reviewed. Reconstruction after esophagectomy was performed using the gastric pull-up (n = 38) or free jejunal graft (n = 14) techniques. The hypopharynx was the most common primary tumor site for the free jejunal graft group, whereas the gastric pull-up group had lesions more frequently in the cervical esophagus (P < 0.05). Both operative time and blood loss in the gastric pull-up group were significantly longer and excessive than those of the free jejunal graft group (P < 0.05). The graft survival rate was 95% (32/34) in the gastric pull-up group and 93% (13/14) for the free jejunal transfer group. The overall leakage rate was 1.9% (1/52). Three patients died (6%) in the postoperative period. There was no significant difference with regard to operative morbidity and mortality between the gastric pull-up group and free jejunal graft group. In conclusion, both free jejunal graft and gastric pull-up are safe and effective methods for the immediate restoration of alimentary continuity.

摘要

本研究的目的是评估下咽及颈段食管癌切除术后胃上提术和游离空肠移植重建术的手术效果。回顾了所有因下咽及颈段食管癌行食管切除术患者的记录。食管切除术后采用胃上提术(n = 38)或游离空肠移植术(n = 14)进行重建。游离空肠移植组最常见的原发肿瘤部位是下咽,而胃上提组颈段食管病变更为常见(P < 0.05)。胃上提组的手术时间和失血量均显著长于且多于游离空肠移植组(P < 0.05)。胃上提组的移植存活率为95%(32/34),游离空肠移植组为93%(13/14)。总渗漏率为1.9%(1/52)。3例患者在术后死亡(6%)。胃上提组和游离空肠移植组在手术并发症和死亡率方面无显著差异。总之,游离空肠移植和胃上提都是立即恢复消化道连续性的安全有效方法。

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