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养老院跌倒预防:一项随机跌倒预防试验的亚组分析

Prevention of falls in nursing homes: subgroup analyses of a randomized fall prevention trial.

作者信息

Rapp Kilian, Lamb Sarah E, Büchele Gisela, Lall Ranjit, Lindemann Ulrich, Becker Clemens

机构信息

Department of Clinical Gerontology, Robert-Bosch Hospital, Stuttgart, Germany.

出版信息

J Am Geriatr Soc. 2008 Jun;56(6):1092-7. doi: 10.1111/j.1532-5415.2008.01739.x. Epub 2008 May 14.

Abstract

OBJECTIVES

To evaluate the effectiveness of a multifactorial fall prevention program in prespecified subgroups of nursing home residents.

DESIGN

Secondary analysis of a cluster-randomized, controlled trial.

SETTING

Six nursing homes in Germany.

PARTICIPANTS

Seven hundred twenty-five long-stay residents; median age 86; 80% female.

INTERVENTION

Staff and resident education on fall prevention, advice on environmental adaptations, recommendation to wear hip protectors, and progressive balance and resistance training.

MEASUREMENTS

Time to first fall and the number of falls. Falls were assessed during the 12-month intervention period. Univariate regression analyses were performed, including a confirmatory test of interaction.

RESULTS

The intervention was more effective in people with cognitive impairment (hazard ratio (HR)=0.49, 95% confidence interval (CI)=0.35-0.69) than in those who were cognitively intact (HR=0.91, 95% CI=0.68-1.22), in people with a prior history of falls (HR=0.47, 95% CI=0.33-0.67) than in those with no prior fall history (HR=0.77, 95% CI=0.58-1.01), in people with urinary incontinence (HR=0.59, 95% CI=0.45-0.77) than in those with no urinary incontinence (HR=0.98, 95% CI=0.68-1.42), and in people with no mood problems (incidence rate ratio (IRR)=0.41, 95% CI=0.27-0.61) than in those with mood problems (IRR=0.74, 95% CI=0.51-1.09).

CONCLUSION

The effectiveness of a multifactorial fall prevention program differed between subgroups of nursing home residents. Cognitive impairment, a history of falls, urinary incontinence, and depressed mood were important in determining response.

摘要

目的

评估多因素预防跌倒计划在疗养院居民特定亚组中的有效性。

设计

对一项整群随机对照试验的二次分析。

地点

德国的六家疗养院。

参与者

725名长期居住居民;中位年龄86岁;80%为女性。

干预措施

对工作人员和居民进行预防跌倒教育、提供环境适应性建议、推荐佩戴髋部保护器以及进行渐进性平衡和阻力训练。

测量指标

首次跌倒时间和跌倒次数。在12个月的干预期内评估跌倒情况。进行单变量回归分析,包括交互作用的验证性检验。

结果

该干预措施在认知障碍患者中(风险比(HR)=0.49,95%置信区间(CI)=0.35 - 0.69)比认知功能正常者(HR = 0.91,95% CI = 0.68 - 1.22)更有效;在有跌倒史的人群中(HR = 0.47,95% CI = 0.33 - 0.67)比无跌倒史者(HR = 0.77,95% CI = 0.58 - 1.01)更有效;在尿失禁患者中(HR = 0.59,95% CI = 0.45 - 0.77)比无尿失禁者(HR = 0.98,95% CI = 0.68 - 1.42)更有效;在无情绪问题的人群中(发病率比(IRR)= 0.41,95% CI = 0.27 - 0.61)比有情绪问题者(IRR = 0.74,95% CI = 0.51 - 1.09)更有效。

结论

多因素预防跌倒计划在疗养院居民亚组中的有效性存在差异。认知障碍、跌倒史、尿失禁和情绪低落对反应的决定作用很重要。

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