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空肠弯曲菌相关性肝炎和心肌损伤

[Campylobacter-jejuni-associated hepatitis and myocardial injury].

作者信息

Braun Kay-P, Theissig Franz, Ernst Helmut, May Matthias, Krülls-Münch Jürgen

机构信息

I. Medizinische Klinik, CTK Cottbus, Cottbus.

出版信息

Med Klin (Munich). 2008 May 15;103(5):346-8. doi: 10.1007/s00063-008-1042-y.

Abstract

BACKGROUND

Campylobacter-jejuni infection can lead to different extraintestinal manifestations. Myo-/pericarditis and toxic hepatitis have been reported. A combined appearance has not been described yet.

CASE REPORT

A 22-year-old woman presented with sudden left thoracic pain. An increase in troponin T, creatine kinase and myoglobin was noted. In the absence of signs of myocardial ischemia, the diagnosis of myocarditis was made. The patient reported diarrhea persisting for 5 days. Campylobacter-jejuni could be identified in the feces. On account of rising transaminases, a biopsy of the liver was performed. The histological examination revealed lesions caused by Campylobacter-jejuni.

CONCLUSION

Given the increasing incidence of Campylobacter-jejuni infections, the case presented here should draw the attention to extraintestinal manifestations.

摘要

背景

空肠弯曲菌感染可导致不同的肠外表现。已报道有心肌/心包炎和中毒性肝炎。尚未描述过两者合并出现的情况。

病例报告

一名22岁女性突发左胸痛。肌钙蛋白T、肌酸激酶和肌红蛋白升高。在无心肌缺血迹象的情况下,诊断为心肌炎。患者自述腹泻持续5天。粪便中可检测出空肠弯曲菌。由于转氨酶升高,进行了肝脏活检。组织学检查显示有空肠弯曲菌引起的病变。

结论

鉴于空肠弯曲菌感染的发病率不断上升,本文所述病例应引起对肠外表现的关注。

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