Prospective assessment of cardiovascular events in patients with partial and advanced interatrial conduction delay: a preliminary observation.

INTRODUCTION

Major adverse cardiovascular events (MACE) have been investigated with partial interatrial block (IAB; P wave > or = 110 ms) but not with advanced IAB.

METHODS

Twenty-four advanced IAB and 34 partial IAB patients were followed for 24 months for MACE, change in renal function and death.

RESULTS

Three patients with advanced IAB had myocardial infarction compared to none with partial IAB (p = 0.03). However, overall MACE was not significantly different between groups with an overall low event rate. There was also no difference between change in mean blood urea nitrogen levels and calculated glomerular filtration rates over time.

CONCLUSION

In a preliminary 24-month period, when compared to patients with partial IAB, those with the uncommon, advanced form of IAB do not appear to be overly at increased risk for MACE. However, larger prospective studies are needed to confirm these results in order to appraise other cardiovascular risk factors.