Wu Angela J, Jarzembowski Jason, Morag Yoav, Lucas David R
Department of Pathology, University of Michigan, MI 48109-0054, USA.
Ann Diagn Pathol. 2008 Jun;12(3):204-7. doi: 10.1016/j.anndiagpath.2006.09.001. Epub 2007 Aug 20.
We report a very rare case of Wagner-Meissner neurilemmoma in the cheek of a 10-year-old boy. The tumor presented as a slowly growing soft tissue swelling. Magnetic resonance imaging disclosed a very infiltrative, 9-cm mass involving the subcutis and deep soft tissues of the right cheek. Microscopically, the tumor was unencapsulated and composed almost entirely of well-formed Wagner-Meissner corpuscles that formed confluent sheets, perivascular cuffs, and individual corpuscles percolating through adipose tissue. Compared with the 3 previous reports, which describe circumscribed, encapsulated tumors in adult patients, this case had distinctive clinicopathologic features never reported: presentation in a pediatric patient, location in the head and neck region, and an infiltrative growth pattern.
