Nikolaev V P
Biofizika. 2008 Jan-Feb;53(1):139-50.
The probabilistic model of the development of decompression disease was modified by introducing the corrections into its equation that refine the dependence of the risk of the injury of tissues by gas bubbles on their blood supply and the intensity of nucleation processes. The parameters of the "worst" virtual tissues and theoretical curves were determined that correspond to the empirical data on the cumulative probability of the development of decompression disease symptoms during some procedures of high-altitude decompression. It was shown that the parameters of these hypothetical tissues depend on the final pressure, the physical load, and the duration ofpreoxygenation. The ways of constructing a working hypothesis about the gradation of real body tissues with respect to the parameters determining the risk of their injury by bubbles and developing the method for the theoretical prognosis of the probability of development of decompression disease during any decompression procedure are discussed.
通过在减压病发展的概率模型方程中引入修正项,对该模型进行了改进。这些修正项细化了气泡对组织造成损伤的风险与其血液供应和成核过程强度之间的关系。确定了“最差”虚拟组织的参数和理论曲线,它们与高海拔减压某些过程中减压病症状发展的累积概率的经验数据相对应。结果表明,这些假设组织的参数取决于最终压力、体力负荷和预充氧时间。讨论了构建关于真实身体组织按照决定其被气泡损伤风险的参数进行分级的工作假设的方法,以及开发在任何减压过程中预测减压病发生概率的理论方法。