Mastronardi L, Ferrante L, Lunardi P, Cervoni L, Fortuna A
Department of Neurological Sciences-Neurosurgery, University of Rome La Sapienza, Italy.
Neurosurgery. 1991 Mar;28(3):449-52. doi: 10.1097/00006123-199103000-00021.
We report a case of association of a brain tumor with multiple intestinal polyposis (Turcot's syndrome) and offer a critical analysis of the relevant literature with a view to revising the classification of the syndrome in relation to familial multiple polyposis and Gardner's syndrome. For this purpose, we considered only cases of intestinal polyposis associated with a primary neuroepithelial tumor (medulloblastoma, glioma, or glioblastoma) as originally described by Turcot. Differences emerged, depending on the central nervous system tumor type, which suggests that this neoplastic association may be classified as two distinct syndromes.
我们报告了一例脑肿瘤合并多发性肠息肉病（Turcot综合征）的病例，并对相关文献进行了批判性分析，以期修订该综合征与家族性多发性息肉病和Gardner综合征相关的分类。为此，我们仅考虑了最初由Turcot描述的与原发性神经上皮肿瘤（髓母细胞瘤、神经胶质瘤或胶质母细胞瘤）相关的肠息肉病病例。根据中枢神经系统肿瘤类型出现了差异，这表明这种肿瘤关联可能被分为两种不同的综合征。
