Partial Klüver-Bucy syndrome arising from a multicentric glioblastoma: anatomo-clinical study of a case with unusual involvement of CNS.

The authors describe the case of a patient showing clinical symptoms consistent with a partial Klüver-Bucy syndrome. CT-scan, macroscopic and histological findings showed the presence of a multicentric glioblastoma with almost exclusive involvement of subcortical gray nuclei and white matter. The possible anatomo-clinical correlations of these unusual locations in KBS are discussed. In addition, the authors emphasize that KBS can arise not only from lesions located in the temporal cortex and/or amygdala, but also from strategically located subcortical lesions particularly involving striatal nuclei and subcortical white matter in the insular area.