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单叶主动脉瓣双叶化:一种新的重建方法。

Bicuspidization of the unicuspid aortic valve: a new reconstructive approach.

作者信息

Schäfers Hans-Joachim, Aicher Diana, Riodionycheva Svetlana, Lindinger Angelika, Rädle-Hurst Tanja, Langer Frank, Abdul-Khaliq Hashim

机构信息

Department of Thoracic and Cardiovascular Surgery, University Hospitals of Saarland, Homburg/Saar, Germany.

出版信息

Ann Thorac Surg. 2008 Jun;85(6):2012-8. doi: 10.1016/j.athoracsur.2008.02.081.

Abstract

BACKGROUND

Unicuspid anatomy of the aortic valve is infrequent but may require intervention by age 40 for severe regurgitation. We propose a new repair technique for the regurgitant unicuspid valve by converting it into a bicuspid aortic valve.

METHODS

Between November 2003 and September 2007, 20 patients underwent regurgitant unicuspid aortic valve repair: 13 had aortic regurgitation (AR) and 7 had combined regurgitation and stenosis. Four patients had previously undergone balloon valvuloplasty for critical aortic stenosis. The aim of the repair was to construct a bicuspid valve with two normal commissures and unrestricted cusp motion. The fused cusp tissue was divided anteriorly and a new commissure of normal height was created. Noncoronary and right coronary cusps were extended with autologous pericardium. Concomitant operations included ascending aortic replacement in 7 and resection of subaortic stenosis in 1.

RESULTS

No early or late deaths occurred. Intraoperative echocardiography revealed minimal or no AR in 19 patients. Follow-up was 4 to 47 months. One patient underwent valve re-repair for recurrent and progressive aortic regurgitation 3 years postoperatively. All other valves remained stable throughout the follow-up period. Freedom from relevant aortic insufficiency (> or = II) at 4 years was 77%; freedom from reoperation was 67%; and freedom from valve replacement was 100%.

CONCLUSIONS

The regurgitant unicuspid aortic valve can be repaired successfully and reproducibly by converting it into bicuspid anatomy. The functional results are comparable with those obtained in reconstructed bicuspid aortic valves. With this approach, replacement can be avoided in most patients with regurgitant unicuspid aortic valves.

摘要

背景

主动脉瓣单叶解剖结构并不常见,但对于严重反流患者,可能在40岁之前就需要进行干预。我们提出了一种新的修复技术,通过将反流性单叶瓣膜转变为双叶主动脉瓣来修复反流性单叶瓣膜。

方法

2003年11月至2007年9月期间,20例患者接受了反流性单叶主动脉瓣修复术:13例为主动脉反流(AR),7例为反流合并狭窄。4例患者此前因严重主动脉狭窄接受过球囊瓣膜成形术。修复的目的是构建一个具有两个正常瓣叶连合且瓣叶活动不受限的双叶瓣膜。融合的瓣叶组织在前部进行分割,并创建一个正常高度的新瓣叶连合。用自体心包扩展无冠瓣叶和右冠瓣叶。同期手术包括7例升主动脉置换术和1例主动脉瓣下狭窄切除术。

结果

无早期或晚期死亡病例。术中超声心动图显示19例患者的主动脉反流轻微或无反流。随访时间为4至47个月。1例患者在术后3年因复发性和进行性主动脉反流接受了瓣膜再次修复术。在整个随访期间,所有其他瓣膜均保持稳定。4年时无相关主动脉瓣关闭不全(≥Ⅱ级)的发生率为77%;无需再次手术的发生率为67%;无需瓣膜置换的发生率为100%。

结论

通过将反流性单叶主动脉瓣转变为双叶解剖结构,可以成功且可重复地修复反流性单叶主动脉瓣。其功能结果与重建双叶主动脉瓣的结果相当。采用这种方法,大多数反流性单叶主动脉瓣患者可以避免进行瓣膜置换。

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