Luxon Bruce A
Division of Gastroenterology-Hepatology, University of Iowa, Iowa City, IA 52242, USA.
Gastroenterol Clin North Am. 2008 Jun;37(2):461-78, vii-viii. doi: 10.1016/j.gtc.2008.02.002.
Autoimmune hepatitis (AIH) is an idiopathic hepatitis characterized by inflammation of the liver, presence of autoantibodies, and evidence of increased gamma globulins in the serum. It represents an enigmatic interaction between the immune system, autoantigens, and unknown triggering factors. This article provides a brief summary of the diagnosis of AIH, the natural history of AIH, an approach to the treatment and follow-up of AIH, and the role of liver transplantation in the treatment of AIH.
自身免疫性肝炎(AIH)是一种特发性肝炎,其特征为肝脏炎症、自身抗体的存在以及血清中γ球蛋白升高的证据。它代表了免疫系统、自身抗原和未知触发因素之间神秘的相互作用。本文简要概述了AIH的诊断、AIH的自然病程、AIH的治疗和随访方法以及肝移植在AIH治疗中的作用。