With a little help from my f(X)riends!: the basis of Ad5-mediated transduction of the liver revealed.
作者信息
Lowenstein Pedro R
机构信息
Board of Governors' Gene Therapeutics Research Institute, Cedars-Sinai Medical Center, and Department of Pharmacology, University of California, Los Angeles, California 90048, USA.
出版信息
Mol Ther. 2008 Jun;16(6):1004-6. doi: 10.1038/mt.2008.80.
Abstract
摘要
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With a little help from my f(X)riends!: the basis of Ad5-mediated transduction of the liver revealed.在我的f(X)riends的一点帮助下：揭示了腺病毒5介导的肝脏转导的基础。 （注：这里“f(X)riends”表述比较奇特，可能存在特定语境含义未明确，按字面翻译如此）
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Adenovirus serotype 5 hexon mediates liver gene transfer.腺病毒5型六邻体介导肝脏基因转移。
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Comparison of adenoviruses from species B, C, E, and F after intravenous delivery.静脉注射后B、C、E和F种腺病毒的比较。
Mol Ther. 2007 Dec;15(12):2146-53. doi: 10.1038/sj.mt.6300319. Epub 2007 Sep 25.
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Fiber shaft-chimeric adenovirus vectors lacking the KKTK motif efficiently infect liver cells in vivo.缺乏KKTK基序的纤维轴嵌合腺病毒载体在体内能有效感染肝细胞。
J Virol. 2007 Nov;81(22):12249-59. doi: 10.1128/JVI.01584-07. Epub 2007 Sep 12.
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Engineering targeted viral vectors for gene therapy.工程化用于基因治疗的靶向病毒载体。
Nat Rev Genet. 2007 Aug;8(8):573-87. doi: 10.1038/nrg2141. Epub 2007 Jul 3.
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