Winterkorn Jacqueline M S, Mack Prinze, Eggenberger Eric
Department of Ophthalmology, New York Presbyterian Hospital - Weill Cornell Medical Center, New York, NY, USA.
Surv Ophthalmol. 2008 May-Jun;53(3):301-5. doi: 10.1016/j.survophthal.2008.02.007.
A 60-year-old man after 5 years of recurrent episodic amaurosis fugax, always resolving, experienced an incident of visual loss that was permanent. Computed tomography and magnetic resonance imaging were normal. Transesophageal echocardiogram and carotid duplex scan ruled out embolic sources from the heart and neck vessels. Blood tests for hypercoagulability found elevated APTT not correcting with 50:50 dilution with control serum, owing to the presence of a lupus anticoagulant. The patient was treated with warfarin, baby aspirin, and a calcium channel blocker and has not had a recurrence of permanent visual loss in 17 years.
一名60岁男性，在经历了5年反复发作的一过性黑矇（每次均自行缓解）后，出现了一次永久性视力丧失。计算机断层扫描和磁共振成像结果正常。经食管超声心动图和颈动脉双功扫描排除了心脏和颈部血管的栓子来源。针对高凝状态的血液检查发现，活化部分凝血活酶时间（APTT）升高，用对照血清按1:1稀释后仍未纠正，原因是存在狼疮抗凝物。该患者接受了华法林、小剂量阿司匹林和一种钙通道阻滞剂治疗，17年来未再出现永久性视力丧失。
