Thibault F, Rixe O, Meric J-B, Renard-Penna R, Boostan H, Mozer P, Comperat E, Richard F, Bitker M-O
Service d'urologie, d'oncologie médicale de radiologie et de pathologie, hôpital de la Pitié-Salpêtrière, université Pierre-et-Marie-Curie, 47, boulevard de l'Hôpital, 75013 Paris, France.
Prog Urol. 2008 Apr;18(4):256-8. doi: 10.1016/j.purol.2008.01.002. Epub 2008 May 2.
A 73-year-old man presented with renal cell carcinoma of the left kidney. Despite the absence of metastases, primary nephrectomy was not performed immediately due to the large tumour volume and the presence of large lymph node extension. The patient was treated with sunitinib for 10 months. Computed tomography at the end of treatment showed a significant reduction of the size of the tumour and the volume of lymph node extension. Radical nephrectomy was then performed. On histological evaluation, the primary renal tumour and, to a lesser degree, the lymph nodes were predominantly necrotic.
一名73岁男性因左肾肾细胞癌就诊。尽管没有转移，但由于肿瘤体积大且存在广泛的淋巴结转移，未立即进行根治性肾切除术。该患者接受了10个月的舒尼替尼治疗。治疗结束时的计算机断层扫描显示肿瘤大小和淋巴结转移体积显著减小。随后进行了根治性肾切除术。组织学评估显示，原发性肾肿瘤以及程度较轻的淋巴结主要为坏死。
