Main Penelope, Robinson Maxine
Utilisation Sub-Committee Secretariat, Department of Health and Ageing, Australia.
Pharmacoepidemiol Drug Saf. 2008 Sep;17(9):861-8. doi: 10.1002/pds.1605.
To examine the impact of publication of the findings of the Women's Health Initiative (WHI) on the utilisation of hormone replacement therapy (HRT) in Australia with particular reference to the influence that media may have had on prescriber and consumer behaviour.
Retrospective data from the Australian Government Department of Health, Ageing DUSC Database and media hits from Factiva were reviewed to obtain prescription numbers, total cost and cost to the pharmaceutical benefits scheme and number of media hits from the year before publication of the combined HRT arm of the WHI.
Prescribing of HRT products decreased significantly immediately following publication of the combined HRT arm of the WHI and continued to decline at a slower rate following publication of the memory and oestrogen only arms of the study.
These results represent a more accurate national estimate of the change in HRT use in Australian women relative to previous findings from surveys carried out in Australia.
研究妇女健康倡议（WHI）研究结果的公布对澳大利亚激素替代疗法（HRT）使用情况的影响，特别关注媒体对开处方者和消费者行为可能产生的影响。
回顾了澳大利亚政府卫生部、老龄化与社区服务部数据库的回顾性数据以及来自Factiva的媒体报道，以获取WHI联合激素替代疗法组公布前一年的处方数量、总成本、药品福利计划成本以及媒体报道数量。
WHI联合激素替代疗法组公布后，HRT产品的处方量立即显著下降，在该研究仅关于记忆力和雌激素的部分公布后，处方量继续以较慢速度下降。
与澳大利亚之前的调查结果相比，这些结果更准确地反映了澳大利亚女性使用HRT的变化情况。
