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腰椎间盘置换术:一项批判性综述。

Lumbar disc arthroplasty: a critical review.

作者信息

Resnick Daniel K, Watters William C

机构信息

Department of Neurosurery, University of Wisconsin School of Medicine, Madison, Wisconsin, USA.

出版信息

Clin Neurosurg. 2007;54:83-7.

Abstract

Lumbar disc arthroplasty may be the most innovative and exciting development in the history of spinal surgery. Manufacturers and proponents cite the ability of these devices to relieve pain while preserving motion at the disc space. The preservation of motion is hypothesized to lower the risk of adjacent segment disease and, thereby, improve long-term outcomes. However, the devices are expensive and their use is associated with the potential for significant complications above and beyond those seen with lumbar fusion. At the present time, there is no evidence to suggest that the use of disc arthroplasty results in better short- or long-term functional outcomes than fusion in properly selected patients. Furthermore, there is little if any evidence to support the hypothesis that adjacent segment degeneration is an important clinical entity. Although the absence of proof is not the same as the proof of absence, greater efficacy must be demonstrated to offset the increased costs and complications associated with these devices. Therefore, these devices require further long-term study in a controlled environment before widespread application.

摘要

腰椎间盘置换术可能是脊柱外科史上最具创新性且令人兴奋的进展。制造商及其支持者称,这些装置能够在保留椎间盘间隙活动度的同时缓解疼痛。保留活动度被认为可降低相邻节段疾病的风险,从而改善长期疗效。然而,这些装置价格昂贵,且使用它们会带来一些严重并发症的风险,这些并发症比腰椎融合术所出现的更为严重。目前,没有证据表明在恰当选择的患者中,椎间盘置换术的短期或长期功能疗效优于融合术。此外,几乎没有证据支持相邻节段退变是一个重要临床实体这一假说。虽然缺乏证据并不等同于不存在证据,但必须证明其有更高的疗效,以抵消与这些装置相关的成本增加和并发症。因此,在广泛应用之前,这些装置需要在可控环境中进行进一步的长期研究。

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