正常眼压性青光眼患者的中央角膜厚度

Central corneal thickness in patients with normal-tension glaucoma.

作者信息

Konareva-Kostianeva Marieta I, Atanassov Marin A

机构信息

Department of Ophthalmology, Medical University, Plovdiv, Bulgaria.

出版信息

Folia Med (Plovdiv). 2007;49(3-4):36-41.

PMID:18504932

Abstract

PURPOSE

To compare the central corneal thickness of eyes with proved normal-tension glaucoma with that of eyes without glaucoma.

DESIGN

A prospective study.

METHODS

The study included 30 consecutive patients with normal-tension glaucoma (60 eyes, group I), and 30 age- and gender-matched non-glaucoma patients (60 eyes, group II). Central corneal thickness was measured using an ultrasonic pachymeter (Pach IV, Accutome). The mean central corneal thickness of normal-tension glaucoma patients and controls were compared using independent samples t-test.

RESULTS

The mean (+/- SD) central corneal thickness of normal-tension glaucoma and non-glaucoma patients was 517.4 +/- 19.2 microm and 549.0 +/- 39.4 microm, respectively. There was a significant difference in this parameter between the groups (P < 0.001). The mean intraocular pressure was higher in glaucomatous eyes (17.1 +/- 2.3 vs. 16.3 +/- 1.4 mm Hg, P = 0.028). The visual acuity in normal-tension glaucoma eyes was lower than that in controls, but the difference failed to reach statistical significance (P = 0.069).

CONCLUSIONS

The results indicate that corneas of patients with normal-tension glaucoma are thinner than those of non-glaucoma patients.

摘要

目的

比较确诊为正常眼压性青光眼的眼睛与无青光眼的眼睛的中央角膜厚度。

设计

一项前瞻性研究。

方法

该研究纳入了30例连续的正常眼压性青光眼患者（60只眼，I组），以及30例年龄和性别匹配的非青光眼患者（60只眼，II组）。使用超声角膜测厚仪（Pach IV，Accutome）测量中央角膜厚度。采用独立样本t检验比较正常眼压性青光眼患者和对照组的平均中央角膜厚度。

结果

正常眼压性青光眼患者和非青光眼患者的平均（±标准差）中央角膜厚度分别为517.4±19.2微米和549.0±39.4微米。两组之间该参数存在显著差异（P<0.001）。青光眼患者的平均眼压较高（17.1±2.3对16.3±1.4毫米汞柱，P = 0.028）。正常眼压性青光眼患者的视力低于对照组，但差异未达到统计学意义（P = 0.069）。