（-）-柯里拉京的全合成。
Total synthesis of (-)-corilagin.
作者信息
Yamada Hidetoshi, Nagao Kohei, Dokei Kazutoyo, Kasai Yusuke, Michihata Naoki
机构信息
School of Science and Technology, Kwansei Gakuin University, Sanda 669-1337, Japan.
出版信息
J Am Chem Soc. 2008 Jun 18;130(24):7566-7. doi: 10.1021/ja803111z. Epub 2008 May 28.
PMID:18505255
Abstract
The synthesis of corilagin was achieved by the integration of the development of the oxidative coupling of the symmetrically protected gallates and the temporarily ring-opened synthetic route for the 3,6-hexahydroxydiphenoyl (HHDP) bridge. This is the first total synthesis of the 1C4/B-ellagitannins, which contain ring-flipped glucose.
摘要
通过对称保护没食子酸酯的氧化偶联开发与3,6 - 六羟基二苯甲酰基（HHDP）桥的临时开环合成路线相结合，实现了柯里拉京的合成。这是首次全合成含有环翻转葡萄糖的1C4/B - 鞣花单宁。
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