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No evidence of cardiac iron in 20 never- or minimally-transfused patients with thalassemia intermedia.

作者信息

Origa Raffaella, Barella Susanna, Argiolas Giovanni Maria, Bina Patrizio, Agus Annalisa, Galanello Renzo

出版信息

Haematologica. 2008 Jul;93(7):1095-6. doi: 10.3324/haematol.12484. Epub 2008 May 27.

DOI:10.3324/haematol.12484
PMID:18508795
Abstract
摘要

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No evidence of cardiac iron in 20 never- or minimally-transfused patients with thalassemia intermedia.20例中间型地中海贫血从未输血或极少输血患者未发现心脏铁沉积证据。
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2
Magnetic resonance evaluation of hepatic and myocardial iron deposition in transfusion-independent thalassemia intermedia compared to regularly transfused thalassemia major patients.与定期输血的重型地中海贫血患者相比，中间型非输血依赖型地中海贫血患者肝脏和心肌铁沉积的磁共振评估
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The uses and differences of r2 and r2* in the determination of iron overload in iron loaded thalassemia patients.R2和R2*在铁过载地中海贫血患者铁过载测定中的应用及差异
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Pituitary iron and volume predict hypogonadism in transfusional iron overload.垂体铁含量和体积可预测输血性铁过载中的性腺功能减退症。
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T2* MRI in regularly transfused children with thalassemia intermedia: serum ferritin does not reflect liver iron stores.中间型地中海贫血定期输血患儿的T2*磁共振成像：血清铁蛋白不能反映肝脏铁储备。
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Observational study of iron overload as assessed by magnetic resonance imaging in an adult population of transfusion-dependent patients with beta thalassaemia: significant association between low cardiac T2* < 10 ms and cardiac events.磁共振成像评估铁过载在依赖输血的β地中海贫血成年患者中的观察性研究：低心脏 T2*<10ms 与心脏事件之间存在显著关联。
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Iron-Loading Anemias.铁负荷性贫血
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Prospective Assessment of Cardiac Iron Deposition, Morphology, and Function by Magnetic Resonance Imaging in Non-Transfusion-Dependent and Neo-Transfusion-Dependent Thalassemia.通过磁共振成像对非输血依赖型和新输血依赖型地中海贫血患者心脏铁沉积、形态及功能的前瞻性评估
J Clin Med. 2025 Jun 6;14(12):4020. doi: 10.3390/jcm14124020.
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Multiparametric cardiac magnetic resonance in patients with thalassemia intermedia: new insights from the E-MIOT network.
中间型地中海贫血患者的心脏磁共振多参数成像：E-MIOT 网络的新见解。
Radiol Med. 2024 Jun;129(6):879-889. doi: 10.1007/s11547-024-01821-y. Epub 2024 Apr 29.
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Impact of genotype on multi-organ iron and complications in patients with non-transfusion-dependent β-thalassemia intermedia.基因型对非输血依赖型β-中间型地中海贫血患者多器官铁沉积及并发症的影响。
Ann Hematol. 2024 Jun;103(6):1887-1896. doi: 10.1007/s00277-024-05741-9. Epub 2024 Apr 6.
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Phenotypic Clustering of Beta-Thalassemia Intermedia Patients Using Cardiovascular Magnetic Resonance.利用心血管磁共振成像对中间型β地中海贫血患者进行表型聚类分析
J Clin Med. 2023 Oct 24;12(21):6706. doi: 10.3390/jcm12216706.
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Erythroferrone exacerbates iron overload and ineffective extramedullary erythropoiesis in a mouse model of β-thalassemia.促红细胞生成素铁蛋白在β-地中海贫血小鼠模型中加剧铁过载和无效的骨髓外红细胞生成。
Blood Adv. 2023 Jul 25;7(14):3339-3349. doi: 10.1182/bloodadvances.2022009307.
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Thalassemia Intermedia: Chelator or Not?中间型地中海贫血：螯合剂治疗，还是不治疗？
Int J Mol Sci. 2022 Sep 5;23(17):10189. doi: 10.3390/ijms231710189.
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Subclinical Left Ventricular Dysfunction in Children and Adolescence With Thalassemia Intermedia.中间型地中海贫血患儿及青少年的亚临床左心室功能障碍
Front Pediatr. 2022 Jun 17;10:774528. doi: 10.3389/fped.2022.774528. eCollection 2022.
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The Link of Pancreatic Iron with Glucose Metabolism and Cardiac Iron in Thalassemia Intermedia: A Large, Multicenter Observational Study.中间型地中海贫血患者胰腺铁与葡萄糖代谢及心脏铁的关联：一项大型多中心观察性研究
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