Reséndiz-Aparicio J C, Coiscou-Domínguez N R, Yáñez-Acosta L, Rodríguez-Rodríguez E, Rivera-Quintero J, Aguirre-García E, Cruz-Martínez E
Departamento de Neurología Pediátrica, Hospital Psiquiátrico Infantil Dr. Juan N. Navarro, Tlalpan, México.
Rev Neurol. 2008;46(11):660-3.
Abnormalities are often observed in the electrical activity of the brain in patients with brain dysfunction.
We conducted a retrospective analysis of the results of electroencephalogram studies carried out between August and December 2006 on children who had been clinically diagnosed with a psychiatric disorder, without taking into account those with epilepsy.
A total of 1000 electroencephalogram (EEG) studies were reviewed; the age of the patients ranged from 0 to 18 years, with an average of 9.7 years, and the ratio between sexes was 67.9% males and 32.1% females. The four most frequently observed psychiatric disorders were: attention deficit hyperactivity disorder, 422; depressive disorder, 103; mental retardation, 99; and behavioural disorder, 96. The EEG findings were divided into normal (37.8%) and abnormal patterns (61.9%). The most frequent abnormality was bioelectric immaturity (56.4% of cases). On analysing epileptiform activities, we found 26 studies (2.6%) and evidence of cortico-subcortical irritability in 6.7%. The total number of children with epileptiform patterns was 71. The most common pattern was the sharp wave (97.2%) and the most frequent location was the temporal lobe (42.3%).
A high percentage of patients with psychiatric disorders also have abnormalities in the electrical activity of their brains, and even epileptiform activity. Electrical abnormalities in the general population of healthy children have been reported in the literature, but the figures that we found are higher for patients with psychiatric disorders. Functioning of the neurons is incorrect and this results in a range of different pathologies. The repercussion of abnormal electrical activity of the brain on the clinical data of the patients is open to discussion, and we consider it to be an epiphenomenon.
脑功能障碍患者的大脑电活动常出现异常。
我们对2006年8月至12月期间对临床诊断为精神障碍的儿童进行的脑电图研究结果进行了回顾性分析，未将癫痫患者纳入考虑。
共回顾了1000份脑电图（EEG）研究；患者年龄从0岁至18岁不等，平均年龄为9.7岁，男女比例为男性67.9%，女性32.1%。最常观察到的四种精神障碍为：注意力缺陷多动障碍，422例；抑郁症，103例；智力障碍，99例；行为障碍，96例。脑电图结果分为正常（37.8%）和异常模式（61.9%）。最常见的异常是生物电不成熟（占病例的56.4%）。在分析癫痫样活动时，我们发现26项研究（2.6%）以及6.7%的皮质-皮质下激惹证据。有癫痫样模式的儿童总数为71例。最常见的模式是尖波（97.2%），最常见的部位是颞叶（42.3%）。
高比例的精神障碍患者大脑电活动也存在异常，甚至有癫痫样活动。文献中已报道健康儿童总体人群存在电异常，但我们发现精神障碍患者的比例更高。神经元功能不正确，这导致了一系列不同的病理情况。大脑异常电活动对患者临床数据的影响有待讨论，我们认为这是一种附带现象。
