Volchegorskiĭ I A, Novoselov P N, Bolotov A A
Probl Tuberk Bolezn Legk. 2008(4):28-32.
The authors have studied whether an indirect clinical-and-laboratory assessment of the extent of a destructive process in the tuberculous infiltrates and that of concomitant pleural affection can be made from the values of the lipid peroxidation-antioxidative defense (PLO-AOD) system in the blood of patients with infiltrative pulmonary tuberculosis (IPT). Regression analysis has indicated that PLO-AOD values significantly reflect the extent of X-ray verified destructions in the tuberculous infiltrates, concomitant pleural involvements, the specific features of immunity of patients with IPT. The neural network technology used to analyze the baseline PLO-AOD values has been ascertained to permit a reliable prognosis of decay cavity closure 4 months after the initiation of medical treatment and of a need for surgical treatment for IPT.
作者研究了能否根据浸润性肺结核（IPT）患者血液中脂质过氧化-抗氧化防御（PLO-AOD）系统的值，对结核浸润中破坏过程的程度以及伴随的胸膜病变进行间接的临床和实验室评估。回归分析表明，PLO-AOD值能显著反映经X线证实的结核浸润破坏程度、伴随的胸膜受累情况以及IPT患者免疫的特异性特征。已确定，用于分析基线PLO-AOD值的神经网络技术能够可靠地预测药物治疗开始4个月后空洞闭合的情况以及IPT患者是否需要手术治疗。
