近期发表的论文：能否少一点通气，多一点氧气？
Recently published papers: a little less ventilation, a little more oxygen please?
作者信息
Ball Jonathan
机构信息
General Intensive Care Unit, St George's Hospital, London SW17 0QT, UK.
出版信息
Crit Care. 2008;12(3):152. doi: 10.1186/cc6898. Epub 2008 May 27.
Abstract
Recent papers discussed include two large, multicentre, high-positive end-expiratory pressure trials in acute lung injury and reflects upon the usefulness of such trial designs. Further papers considered include the emerging story of beta2-agonists for pulmonary oedema, highlights the newly described, iatrogenic demon, of ventilator-induced diaphragm injury, promotes the addition of B-type natriuretic peptide testing to the prediction of extubation success, and muses again over the oxygen debate.
摘要
近期讨论的论文包括两项针对急性肺损伤的大型多中心高呼气末正压试验，并对这类试验设计的实用性进行了反思。其他被考虑的论文包括β2受体激动剂治疗肺水肿的新进展，强调了新描述的医源性问题——呼吸机诱发的膈肌损伤，提倡增加B型利钠肽检测以预测拔管成功率，以及再次思考氧气相关的争论。
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Recently published papers: a little less ventilation, a little more oxygen please?近期发表的论文：能否少一点通气，多一点氧气？
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本文引用的文献
1
Changes in B-type natriuretic peptide improve weaning outcome predicted by spontaneous breathing trial.B型利钠肽的变化可改善由自主呼吸试验预测的撤机结果。
Crit Care Med. 2008 May;36(5):1421-6. doi: 10.1097/CCM.0b013e31816f49ac.
2
Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans.机械通气患者膈肌纤维的快速废用性萎缩
N Engl J Med. 2008 Mar 27;358(13):1327-35. doi: 10.1056/NEJMoa070447.
3
Positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome: a randomized controlled trial.急性肺损伤和急性呼吸窘迫综合征成人患者呼气末正压设置：一项随机对照试验。
JAMA. 2008 Feb 13;299(6):646-55. doi: 10.1001/jama.299.6.646.
4
Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled trial.采用低潮气量、肺复张手法及高呼气末正压通气策略治疗急性肺损伤和急性呼吸窘迫综合征：一项随机对照试验
JAMA. 2008 Feb 13;299(6):637-45. doi: 10.1001/jama.299.6.637.
5
Terbutaline lessens protein fluxes across the alveolo-capillary barrier during high-volume ventilation.
Intensive Care Med. 2008 Apr;34(4):763-70. doi: 10.1007/s00134-007-0954-y. Epub 2007 Dec 18.
6
Effects of ventilation with 100% oxygen during early hyperdynamic porcine fecal peritonitis.早期高动力性猪粪性腹膜炎期间100%氧气通气的影响
Crit Care Med. 2008 Feb;36(2):495-503. doi: 10.1097/01.CCM.0B013E318161FC45.
7
Aerosolized salbutamol accelerates the resolution of pulmonary edema after lung resection.雾化沙丁胺醇可加速肺切除术后肺水肿的消退。
Chest. 2008 Apr;133(4):845-52. doi: 10.1378/chest.07-1710. Epub 2007 Nov 7.
8
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