Rapley J W, Brunsvold M A
Department of Periodontics, Wilford Hall USAF Medical Center, Lackland AFB, TX.
J Periodontol. 1991 Feb;62(2):132-4. doi: 10.1902/jop.1991.62.2.132.
This study was conducted to determine if erythrosine had any effect when placed in contact with alveolar bone and gingival connective tissue in dogs in conjunction with a periodontal surgical procedure. Periodontal surgery was performed on 15 dogs, with a mucoperiosteal flap affording access for introduction of erythrosine (test) or saline (control) solutions, and subsequent flap replacement. The dogs were sacrificed at 2, 7, 10, 14, 21, and 28 days. Autopsy specimens were prepared, stained, sectioned, and examined by light microscopy. The general amount, degree, and type of inflammatory infiltrate was evaluated and recorded. Erythrosine had no apparent effect on the clinical healing time, alveolar bone, or gingival connective tissue in regard to the general degree, type, and location of the inflammation infiltrate based on postsurgical observations.
本研究旨在确定在犬类进行牙周手术时，赤藓红与牙槽骨和牙龈结缔组织接触后是否有任何影响。对15只犬进行了牙周手术，制作黏骨膜瓣以便注入赤藓红（试验组）或生理盐水（对照组）溶液，随后将瓣复位。在术后第2、7、10、14、21和28天处死这些犬。制备尸检标本，进行染色、切片，并通过光学显微镜检查。评估并记录炎症浸润的总体数量、程度和类型。根据术后观察，就炎症浸润的总体程度、类型和位置而言，赤藓红对临床愈合时间、牙槽骨或牙龈结缔组织没有明显影响。
