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植物细胞悬浮培养物中烟酸的代谢,IV:烟酸N-α-阿拉伯糖苷的存在与代谢(作者译)

[Metabolism of nicotinic acid in plant cell suspension cultures, IV: Occurrence and metabolism of nicotinic acid N-alpha-arabinoside (author's transl)].

作者信息

Leienbach K W, Heeger V, Barz W

出版信息

Hoppe Seylers Z Physiol Chem. 1976 Aug;357(8):1089-95.

PMID:185135
Abstract

Application of nicotinic acid to cell suspension cultures of Petroselinum hortense Hoffm., Daucus carota, Nicotiana tabacum and Nicotiana glauca leads to the formation of the recently isolated[2] nicotinic acid N-alpha-L-arabinoside. In these cell cultures the arabinoside is a metabolically active compound; the nicotinic acid moiety is used for NAD synthesis and nicotinic acid degradation involving decarboxylation and ring fission. N-Methylnicotinic acid (trigonelline) and nicotinic acid N-alpha-L-arabinoside occur alternatively in plant cell suspension cultures, but seem to fulfil the same function as a reserve form for nicotinic acid. Catabolism of nicotinic acid in parsley cell suspension cultures does not involve 6-hydroxynicotinic acid as an intermediate.

摘要

将烟酸应用于园叶柴胡、胡萝卜、烟草和光烟草的细胞悬浮培养物中,会导致最近分离出的[2]烟酸N-α-L-阿拉伯糖苷的形成。在这些细胞培养物中,阿拉伯糖苷是一种具有代谢活性的化合物;烟酸部分用于NAD合成以及涉及脱羧和环裂变的烟酸降解。N-甲基烟酸(胡芦巴碱)和烟酸N-α-L-阿拉伯糖苷在植物细胞悬浮培养物中交替出现,但似乎作为烟酸的储备形式发挥相同的功能。香菜细胞悬浮培养物中烟酸的分解代谢不涉及6-羟基烟酸作为中间体。

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