Obstet Gynecol. 2008 Jun;111(6):1495-502. doi: 10.1097/AOG.0b013e31817d252f.
Genetic testing is poised to play an increasing role in the practice of obstetrics and gynecology. To assure patients of the highest quality of care, physicians should become familiar with the currently available array of genetic tests and the tests' limitations. Clinicians should be able to identify patients within their practices who are candidates for genetic testing. Candidates will include patients who are pregnant or considering pregnancy and are at risk for giving birth to affected children as well as gynecology patients who, for example, may have or be predisposed to certain types of cancer. The purpose of this Committee Opinion is to review some of the ethical issues related to genetic testing and provide guidelines for the appropriate use of genetic tests by obstetrician-gynecologists. Expert consultation and referral are likely to be needed when obstetrician=gynecologists are confronted with these issues.
基因检测在妇产科实践中有望发挥越来越重要的作用。为了向患者确保最高质量的护理,医生应熟悉当前可用的一系列基因检测及其局限性。临床医生应能够在其诊疗范围内识别适合进行基因检测的患者。适合检测的患者将包括怀孕或正在考虑怀孕且有生育患病子女风险的患者,以及例如可能患有或易患某些类型癌症的妇科患者。本委员会意见的目的是审查与基因检测相关的一些伦理问题,并为妇产科医生合理使用基因检测提供指导方针。当妇产科医生面临这些问题时,可能需要专家咨询和转诊。