Rees A P, Meadors M, Ventura H O, Pankey G A
Department of Internal Medicine, Ochsner Clinic, New Orleans, LA 70121.
J Heart Lung Transplant. 1991 Mar-Apr;10(2):329-32.
A pulmonary infection caused by both Toxoplasma gondii and cytomegalovirus (CMV) developed in a heart transplant recipient. A presumptive diagnosis of CMV pneumonitis was made on the basis of a skin biopsy finding demonstrating CMV inclusions. This diagnosis was later supported by a positive pleural fluid culture for CMV, a greater than fourfold increase in CMV IgG antibody, and a response to therapy with ganciclovir sodium. Biopsy of skin lesions in patients at risk for CMV infections may represent an important early diagnostic tool.
一名心脏移植受者发生了由刚地弓形虫和巨细胞病毒（CMV）共同引起的肺部感染。基于皮肤活检发现显示有CMV包涵体，做出了CMV肺炎的初步诊断。随后，CMV胸腔积液培养阳性、CMV IgG抗体增加四倍以上以及对更昔洛韦钠治疗有反应，均支持了这一诊断。对有CMV感染风险的患者进行皮肤病变活检可能是一种重要的早期诊断工具。
