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Hematopoietic stem cell transplantation in Langerhans cell histiocytosis: case report and review of the literature.

作者信息

Kesik Vural, Citak Caglar, Kismet Erol, Koseoglu Vedat, Akyuz Canan

机构信息

Department of Pediatric Oncology, School of Medicine, Gulhane Military Medical Academy, Etlik, Ankara, Turkey.

出版信息

Pediatr Transplant. 2009 May;13(3):371-4. doi: 10.1111/j.1399-3046.2008.00989.x. Epub 2008 Jun 1.

Abstract

The prognosis in children with LCH who do not respond to the conventional therapies is very poor. SCT may be a new approach. However, there are limited data about the results of the transplantations. Herein we report a patient with refractory multisystem LCH who underwent allogeneic bone marrow transplantation and is disease and treatment free 54 months after transplantation. Further studies are required to establish the role of SCT in refractory LCH.

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