Murase Kazuyuki, Matsunaga Takuya, Hayashi Tsuyoshi, Ishiwatari Hirotoshi, Araki Naoko, Iyama Satoshi, Sato Tsutomu, Kobune Masayoshi, Takimoto Rishu, Miyanishi Koji, Miyazaki Toru, Ikeda Hisami, Kato Junji, Niitsu Yoshiro
The Fourth Department of Internal Medicine, Sapporo Medical University, School of Medicine, Sapporo.
Intern Med. 2008;47(11):1033-8. doi: 10.2169/internalmedicine.47.0803. Epub 2008 Jun 2.
We report the second patient diagnosed with autoimmune pancreatitis complicated with autoimmune thrombocytopenia and interstitial pneumonia. The patient was treated with prednisolone and responded favorably. We demonstrated that anti-platelet (PLT) antibody of the patient was IgG4 and that it may react with HLA, not specific antigen, on both pancreas and PLT.
我们报告了第二例被诊断为自身免疫性胰腺炎合并自身免疫性血小板减少症和间质性肺炎的患者。该患者接受泼尼松龙治疗,反应良好。我们证明该患者的抗血小板(PLT)抗体为IgG4,并且它可能与胰腺和血小板上的HLA反应,而非特异性抗原。