Murch S H, Carter E P, Tsagarakis S, Grossman A, Savage M O
Department of Child Health, St. Bartholomew's Hospital, London, UK.
Acta Paediatr Scand. 1991 Feb;80(2):259-61. doi: 10.1111/j.1651-2227.1991.tb11845.x.
An 8-year-old girl presenting in hypoglycaemic coma was shown to have isolated deficiency of adrenocorticotrophic hormone (ACTH) secretion. Failure to secrete ACTH in response to intravenous administration of synthetic ovine corticotrophin-releasing factor (CRF-41) suggests that this disorder was due to a primary pituitary defect, rather than of hypothalamic origin.
一名8岁女孩因低血糖昏迷就诊，检查发现其存在促肾上腺皮质激素（ACTH）分泌孤立性缺乏。静脉注射合成羊促肾上腺皮质激素释放因子（CRF - 41）后未能分泌ACTH，提示该疾病是由原发性垂体缺陷引起，而非下丘脑起源。
