Smith D L, Skuta G L, Lindenmuth K A, Musch D C, Bergstrom T J
Department of Ophthalmology, Bethesda Naval Hospital, Md.
Ophthalmic Surg. 1991 May;22(5):251-5.
Corneal endothelial cell counts were obtained preoperatively and 3 months postoperatively in 46 eyes undergoing glaucoma filtering surgery. Average central endothelial cell loss in eyes without postoperative iridocorneal touch was 1.6%. In eyes with iridocorneal touch (Spaeth's grades 1 and 2), the average cell counts decreased by 7.1% and 9.3%, respectively. The average loss for combined grades 1 and 2 (8.1%) approached statistical significance (P +/- .06). The average loss in two patients with corneolenticular touch (Spaeth's grade 3) was greater than 50%. These findings suggest that early postoperative iridocorneal touch is unlikely to lead to corneal compromise in most eyes, but that corneolenticular touch can result in severe endothelial cell loss.
对46只接受青光眼滤过手术的眼睛在术前和术后3个月进行角膜内皮细胞计数。术后无虹膜角膜接触的眼睛中央内皮细胞平均损失率为1.6%。有虹膜角膜接触（斯派思分级1级和2级）的眼睛，细胞计数平均分别下降了7.1%和9.3%。1级和2级合并的平均损失率（8.1%）接近统计学显著性（P±0.06）。两名有角膜晶状体接触（斯派思分级3级）患者的平均损失率大于50%。这些发现表明，术后早期虹膜角膜接触在大多数眼睛中不太可能导致角膜损害，但角膜晶状体接触可导致严重的内皮细胞损失。
