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希恩综合征合并血小板无力症:病例报告及文献复习

Sheehan's syndrome associated with Glanzmann's Thrombasthenia: case report and literature review.

作者信息

Bayraktaroglu T, Colak N, Nalcaci M, Yenerel M N

机构信息

Department of Endocrinology and Metabolism, Zonguldak Karaelmas University, Medical Faculty, Zonguldak, Istanbul, Turkey.

出版信息

Exp Clin Endocrinol Diabetes. 2008 Oct;116(9):549-53. doi: 10.1055/s-2008-1062726. Epub 2008 Apr 1.

Abstract

OBJECTIVES

We aimed to present a case of Sheehan's syndrome associated with Glanzmann's thrombasthenia.

CASE REPORT

A 41-year-old-woman presented with hemorrhagic diathesis needed blood transfusions occasionally during her life-time. In the course of her second delivery, four units of whole blood transfusion were required to control profuse uterine bleeding and her hemodynamic status. During postpartum period, she was not able to lactate and her menstrual periods did not return. Her hormonal profile revealed gonadotropin, TSH and prolactin deficiencies.

CONCLUSION

According to our knowledge, this is the first case report of hypopituitarism developed after delivery in association with Glanzmann's thromboasthenia-induced severe uterine hemorrhage.

摘要

目的

我们旨在报告一例与Glanzmann血小板无力症相关的席汉综合征病例。

病例报告

一名41岁女性有出血倾向,一生中偶尔需要输血。在她第二次分娩过程中,需要输注4单位全血以控制大量子宫出血和她的血流动力学状态。产后,她无法泌乳,月经也未恢复。她的激素水平显示促性腺激素、促甲状腺激素和催乳素缺乏。

结论

据我们所知,这是首例产后发生的垂体功能减退与Glanzmann血小板无力症所致严重子宫出血相关的病例报告。

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