Stumpf Paul G, Flores Marisol, Murillo Jeremias
Department of Obstetrics and Gynecology, Newark Beth Israel Medical Center, Newark, New Jersey, USA.
Am J Perinatol. 2008 Aug;25(7):413-5. doi: 10.1055/s-2008-1075032. Epub 2008 Jun 4.
Infection with methicillin-resistant Staphylococcus aureus (MRSA) has become a worldwide problem and is no longer acquired only in a hospital setting. Community-associated MRSA is an emerging pathogen of increasing interest to both obstetricians and neonatologists, reported in all three trimesters of pregnancy and postpartum, and in neonatal intensive care units, leading to severe outcomes, including neonatal death. This case report describes a serious and potentially life-threatening infection (including wound abscess, septicemia, septic thrombophlebitis, and septic pulmonary emboli) that developed in an otherwise healthy postpartum woman who had screened positive for MRSA in nares, vagina, and rectum at the time of her prior admission in labor as part of a research study. We conclude that asymptomatic nasal, vaginal, and rectal colonization with MRSA occurs in pregnancy and may be a risk factor for serious systemic infection after delivery.
耐甲氧西林金黄色葡萄球菌（MRSA）感染已成为一个全球性问题，且不再仅在医院环境中获得。社区相关性MRSA是一种新兴病原体，越来越引起产科医生和新生儿科医生的关注，在妊娠的所有三个阶段、产后以及新生儿重症监护病房均有报道，可导致严重后果，包括新生儿死亡。本病例报告描述了一名原本健康的产后妇女发生的严重且可能危及生命的感染（包括伤口脓肿、败血症、脓毒性血栓性静脉炎和脓毒性肺栓塞），该妇女在之前分娩入院作为一项研究的一部分时，鼻腔、阴道和直肠MRSA筛查呈阳性。我们得出结论，妊娠期间会出现无症状的鼻腔、阴道和直肠MRSA定植，这可能是分娩后发生严重全身感染的一个危险因素。
