Ulker Karbeyaz Başak, Miller Eric L, Cleveland Robin O
Analogic Corporation, Peabody, Massachusetts 01960, USA.
J Acoust Soc Am. 2008 May;123(5):2944-56. doi: 10.1121/1.2897045.
A shaped-based ultrasound tomography method is proposed to reconstruct ellipsoidal objects using a linearized scattering model. The method is motivated by the desire to detect the presence of lesions created by high intensity focused ultrasound (HIFU) in applications of cancer therapy. The computational size and limited view nature of the relevant three-dimensional inverse problem renders impractical the use of traditional pixel-based reconstruction methods. However, by employing a shape-based parametrization it is only necessary to estimate a small number of unknowns describing the geometry of the lesion, in this paper assumed to be ellipsoidal. The details of the shape-based nonlinear inversion method are provided. Results obtained from a commercial ultrasound scanner and a tissue phantom containing a HIFU-like lesion demonstrate the feasibility of the approach where a 20 mm x 5 mm x 6 mm ellipsoidal inclusion was detected with an accuracy of around 5%.
提出了一种基于形状的超声层析成像方法，用于使用线性化散射模型重建椭球体对象。该方法的动机是希望在癌症治疗应用中检测高强度聚焦超声（HIFU）产生的病变的存在。相关三维逆问题的计算规模和有限视角性质使得传统的基于像素的重建方法不切实际。然而，通过采用基于形状的参数化，只需要估计少量描述病变几何形状的未知数，本文假设病变为椭球形。提供了基于形状的非线性反演方法的详细信息。从商用超声扫描仪和包含类似HIFU病变的组织模型获得的结果证明了该方法的可行性，其中检测到一个20毫米×5毫米×6毫米的椭球形内含物，精度约为5%。
